Genetically Modified Crops in India : Present Status and Science behind it


GM Crops Currently Allowed in India  

India has approved only a few GM crops for commercial cultivation:  

- Bt Cotton (2002) – The only fully approved GM crop in India, modified to resist bollworm pests.  

- DMH-11 Mustard (2024) – Genetically Modified Hybrid Mustard developed by Delhi University (under review for full approval).  


GM Crops Under Research/Trials  


Several GM crops are in various stages of field trials and regulatory approval:  

- Bt Brinjal (Event EE-1) – Developed by Mahyco, approved in 2009 but put on hold due to protests.  

- Herbicide-Tolerant (HT) Bt Cotton – Unofficially grown in some states but not legally approved.  

- Golden Rice – Vitamin-A enriched rice (under development, not yet approved).  

- GM Potato, Banana, Tomato, and Chickpea – Some are in confined trials for disease resistance and nutrition enhancement.  


Regulatory Bodies for GM Crops in India  

- Genetic Engineering Appraisal Committee (GEAC) – Under the Ministry of Environment, Forest & Climate Change (MoEF&CC), it approves GM crops under the Environment Protection Act (EPA), 1986.  

- Review Committee on Genetic Manipulation (RCGM) – Under the Department of Biotechnology (DBT), monitors research and field trials.  

- Food Safety and Standards Authority of India (FSSAI) – Regulates GM food safety.  


International Conventions Governing GM Crops  

- Cartagena Protocol on Biosafety (2000) – Part of the Convention on Biological Diversity (CBD), regulates transboundary movement of GM organisms (India is a signatory).  

- Codex Alimentarius Commission – Sets global food safety standards, including GM foods.  

- International Treaty on Plant Genetic Resources (ITPGRFA) – Addresses conservation and sustainable use of plant genetic resources, including GM crops.  


 Recent Developments  

- DMH-11 Mustard Approval (2024) – GEAC recommended environmental release, awaiting final government clearance.  

- HT Bt Cotton Controversy – Illegal cultivation reported in Maharashtra and Telangana, prompting crackdowns.  


 Key Genetic Engineering Terms in GM Crops


 (A) Gene Editing & Modification Tools


1. CRISPR-Cas9 – A gene-editing tool allowing precise modification of DNA (used in developing disease-resistant crops).  

2. RNA Interference (RNAi) – Silencing specific genes to control pests (e.g., Bt Brinjal uses RNAi for resistance).  

3. Agrobacterium-mediated Transformation – A bacterium used to transfer desired genes into plants.  


 (B) Selectable Marker Systems

1. Barnase-Barstar System  

   - Barnase – A toxic gene that induces male sterility (used in DMH-11 Mustard).  

   - Barstar – A suppressor gene that restores fertility when needed.  

   - Purpose: Helps in hybrid seed production without manual labor.  


2. Herbicide-Tolerant (HT) Genes  

   - EPSPS (Glyphosate Resistance) – Makes crops resistant to weed-killers like Roundup.  

   - PAT/bar Gene (Glufosinate Resistance) – Used in HT Bt Cotton (illegally grown in India).  


 (C) Pest & Disease Resistance

1. Cry Genes (Bt Toxins)  

   - Cry1Ac, Cry2Ab – Used in Bt Cotton to kill bollworms.  

   - Cry1Fa – Tested in Bt Brinjal for fruit borer resistance.  


2. Virus-Resistant Genes  

   - Papaya Ringspot Virus (PRSV)-Resistant Papaya – Used in GM papaya (approved in the US, not India).  



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